Research

 

Professor Klorman is interested in using brain event-related potentials to aid in understanding cognitive disturbances in Attention Deficit Hyperactivity Disorder and related disturbances. One line of his research utilizes blind trials of methylphenidate and placebo to assess the clinical and cognitive impact of these drugs during information processing. These studies have been conducted with normal subjects as well as patients with a range of comorbid disorders, including dyslexia and aggressive disorders. In particular, the research attempts to identify dysfunctions involving specific aspects of inhibition processes that are aberrant in these conditions and modified by stimulant drugs. In addition, Professor Klorman is collaborating with faculty in the Department of Pediatrics (Tristram Smith and Caroline Magyar) in the prediction of response to early intensive behavioral intervention for children with autism.

 

Recent Publications

 

• Kopecky, H., Chang, H. T., Klorman, R., Thatcher, J. E., & Borgstedt, A. D. (2005). Performance and private speech of children with Attention-Deficit/Hyperactivity Disorder while taking the Tower of Hanoi test: Effects of depth of search, diagnostic subtype, and methylphenidate. Journal of Abnormal Child Psychology, 33, 625-638.
• Gorman, E. B., Klorman, R., Thatcher, J. E., & Borgstedt, A. D. B. (2006). Effects of methylphenidate on subtypes of Attention-Deficit/Hyperactivity Disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 45, 808-816.
• Hazel-Fernandez, L. A., Klorman, R., Wallace, J., & Cook, S. (2006). Methylphenidate improves executive function performance in African American children with Attention-Deficit/Hyperactivity Disorder. Journal of Attention Disorders, 9, 582-589.
• Burgio-Murphy, A., Klorman, R., Thatcher, J. E., Shaywitz, S. E., Fletcher, J. M., Marchione, K. E., Holahan, J. M., Stuebing, K. K., & Shaywitz, B. A. (2007). Event-related potentials during error monitoring in children with Attention-Deficit Hyperactivity Disorder, Oppositional Defiant Disorder, Reading Disorder, and Math Disorder. Biological Psychology, 75, 75-86.

 

Current and Recent Graduate Students

 

• Andrea Burgio: Event-related potentials during error monitoring in children with Attention-Deficit Hyperactivity Disorder, Oppositional Defiant Disorder, Reading Disorder, and Math Disorder
• H. Theresa Chang: Effects of stimulant treatment on planning strategies of children with Attention Deficit Hyperactivity Disorder
• Erin B. Gorman: Effects of methylphenidate on subtypes of Attention-Deficit/Hyperactivity Disorder.
• Leslie Hazel-Fernandez: Acute effects of methylphenidate on cognitive processing in African American children with Attention Deficit Hyperactivity Disorder
• Nora Ilniczky: Effects of methylphenidate on response prevention
• Helena Kopecky: Private speech during problem solving in normal and Attention Deficit Hyperactivity Disorder children
• Deborah Krusch: Effects of repeated secretin administration on cognitive, behavioral, and physiological functioning of children with atypical Pervasive Developmental Disorder

 

Recent Courses Taught

 

• CSP 576 -- Psychopathology II
• CSP 504 -- Data Analysis I
• CSP 309 -- Honors Seminar

 

Grants

 

• STAART Center for the study of Genotype and phenotype of response to treatment of autism, Project 1 (Response to Early Intensive Behavioral Intervention), NIMH, 7-1-02 to 6-30-07.

 

Recent Honors and Distinctions

 

• Member, NIMH Cognition, Emotion and Personality Research Review Committee (1981-1985)
• Member, NIMH Child Psychopathology and Treatment Study Section (1998-1999)
• Member NIH Behavioral and Biobehavioral Processes-6 Study Section (1999-2002)
• Society for Psychophysiological Research, Chair, Young Career Award Review Committee (1996-1999)
• Society for Psychophysiological Research, Bylaws Committee (2002 - 2005); Chair (2003-2005)
• Fellow, American Psychological Society (1997)
• Fellow, Division 6, American Psychological Society (2003)